Gene

exoc7

ID

ZDB-GENE-040426-2752

Name

exocyst complex component 7

Symbol

exoc7 Nomenclature History

Previous Names

zgc:56575 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to be involved in exocytosis. Predicted to localize to exocyst. Orthologous to human EXOC7 (exocyst complex component 7).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56575 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Coulter et al., 2020
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With exoc7 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with seizures and brain atrophy	619072

Associated With exoc7 Via Experimental Models

Human Disease	Fish	Conditions	Citations
microcephaly	exoc7^mh111/mh111	standard conditions	Coulter et al., 2020

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR046364	Exocyst complex subunit Exo70, C-terminal
Family	IPR004140	Exocyst complex component Exo70
Homologous_superfamily	IPR016159	Cullin repeat-like-containing domain superfamily

Domain Details Per Protein

Protein	Length	Cullin repeat-like-containing domain superfamily	Exocyst complex component Exo70	Exocyst complex subunit Exo70, C-terminal
UniProtKB:U3JAX5 InterPro	695
UniProtKB:A0A8M2BKA5 InterPro	686
UniProtKB:U3JAN6 InterPro	652
UniProtKB:A0A8M3AYR4 InterPro	690
UniProtKB:A0A8M9Q897 InterPro	677
UniProtKB:Q7ZTX5 InterPro	673
UniProtKB:A0A8M2BKR2 InterPro	665
UniProtKB:A0A8M2BK81 InterPro	686
UniProtKB:A0A2R8QNA9 InterPro	703
UniProtKB:A0A286Y9B1 InterPro	699
UniProtKB:U3JB38 InterPro	682

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	exoc7-201 (1) Ensembl	Ensembl	2,279 nt	Select Tool ZFIN BLAST
mRNA	exoc7-202 (1) Ensembl	Ensembl	3,024 nt	Select Tool ZFIN BLAST
mRNA	exoc7-203 (1) Ensembl	Ensembl	2,071 nt	Select Tool ZFIN BLAST
mRNA	exoc7-204 (1) Ensembl	Ensembl	2,571 nt	Select Tool ZFIN BLAST
mRNA	exoc7-205 (1) Ensembl	Ensembl	267 nt	Select Tool ZFIN BLAST
mRNA	exoc7-206 (1) Ensembl	Ensembl	2,216 nt	Select Tool ZFIN BLAST
mRNA	exoc7-207 (1) Ensembl	Ensembl	2,961 nt	Select Tool ZFIN BLAST
mRNA	exoc7-208 (1) Ensembl	Ensembl	2,973 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations